Concentrate (by cancer cells)

Italian translation: concentrate/i (tramite/per mezzo di cellule cancerogene/tumorali)

15:57 Dec 21, 2023
English to Italian translations [PRO]
Medical - Medical (general)
English term or phrase: Concentrate (by cancer cells)
Hello,
I am going through a clinical study.
I would like to know how to translate 'concentrate' here, as in 'artemisinin could be selectively picked up and concentrated by cancer cells'.
I wonder if it means 'isolated' or if the preposition 'by' may be wrong.
Thank you!
CristianaITA
Italian translation:concentrate/i (tramite/per mezzo di cellule cancerogene/tumorali)
Explanation:
I recettori CD40 sono normalmente dispersi sulla superficie delle cellule immunitarie in riposo, ma devono essere concentrati e raggruppati in complessi altamente organizzati al fine di innescare una risposta immunitaria contro il cancro.
https://blogpinali.wordpress.com/2018/04/22/scoperto-recetto...

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Note added at 4 giorni (2023-12-26 15:44:37 GMT) Post-grading
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Figurati Cristiana
Selected response from:

Francesco Badolato
Italy
Local time: 15:29
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1Concentrated
Fausto Menegozzo
3concentrate/i (tramite/per mezzo di cellule cancerogene/tumorali)
Francesco Badolato


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
concentrate (by cancer cells)
Concentrated


Explanation:
This excerpt could clarify it: "Cancer cells express a large concentration of cell surface transferrin receptors that facilitate uptake of the plasma iron-carrying protein transferrin via endocytosis. By covalently tagging artemisinin to transferrin, artemisinin could be selectively picked up and concentrated by cancer cells." I think that the meaning of 'concentrated', in this context could be the following: "to accumulate (a toxic substance) in bodily tissues
Fish concentrate mercury." (as per Merriam-Webster).

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Note added at 2 days 23 hrs (2023-12-24 15:28:57 GMT)
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concentrato/accumulato


    https://pubmed.ncbi.nlm.nih.gov/16185154/#:~:text=Cancer%20cells%20express%20a%20large,and%20concentrated%20by%20cancer%20cells.
    https://www.merriam-webster.com/dictionary/concentrate
Fausto Menegozzo
United States
Local time: 06:29
Specializes in field
Native speaker of: Native in ItalianItalian
Notes to answerer
Asker: Salve Fausto, il concetto isolatamente sembrerebbe corretto, ma nel contesto non lo capisco. "E' stato possibile incrementare selettivamente il livello di artemisinina e... accumulata dalle cellule cancerogene"? Ho sbaglio io (possibile, non è il mio campo), oppure c'è un errore nel testo. Grazie.


Peer comments on this answer (and responses from the answerer)
agree  Costanza D'Odorico
39 mins
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2 days 41 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
concentrate (by cancer cells)
concentrate/i (tramite/per mezzo di cellule cancerogene/tumorali)


Explanation:
I recettori CD40 sono normalmente dispersi sulla superficie delle cellule immunitarie in riposo, ma devono essere concentrati e raggruppati in complessi altamente organizzati al fine di innescare una risposta immunitaria contro il cancro.
https://blogpinali.wordpress.com/2018/04/22/scoperto-recetto...

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Note added at 4 giorni (2023-12-26 15:44:37 GMT) Post-grading
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Figurati Cristiana

Francesco Badolato
Italy
Local time: 15:29
Works in field
Native speaker of: Native in ItalianItalian
PRO pts in category: 395
Notes to answerer
Asker: Grazie Francesco per la spiegazione.

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