https://www.proz.com/kudoz/english-to-italian/medical-general/7167394-concentrate-by-cancer-cells.html
Dec 21, 2023 15:57
5 mos ago
17 viewers *
English term

Concentrate (by cancer cells)

English to Italian Medical Medical (general)
Hello,
I am going through a clinical study.
I would like to know how to translate 'concentrate' here, as in 'artemisinin could be selectively picked up and concentrated by cancer cells'.
I wonder if it means 'isolated' or if the preposition 'by' may be wrong.
Thank you!

Proposed translations

2 days 41 mins
Selected

concentrate/i (tramite/per mezzo di cellule cancerogene/tumorali)

I recettori CD40 sono normalmente dispersi sulla superficie delle cellule immunitarie in riposo, ma devono essere concentrati e raggruppati in complessi altamente organizzati al fine di innescare una risposta immunitaria contro il cancro.
https://blogpinali.wordpress.com/2018/04/22/scoperto-recetto...

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Note added at 4 giorni (2023-12-26 15:44:37 GMT) Post-grading
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Figurati Cristiana
Note from asker:
Grazie Francesco per la spiegazione.
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4 KudoZ points awarded for this answer.
+1
2 hrs

Concentrated

This excerpt could clarify it: "Cancer cells express a large concentration of cell surface transferrin receptors that facilitate uptake of the plasma iron-carrying protein transferrin via endocytosis. By covalently tagging artemisinin to transferrin, artemisinin could be selectively picked up and concentrated by cancer cells." I think that the meaning of 'concentrated', in this context could be the following: "to accumulate (a toxic substance) in bodily tissues
Fish concentrate mercury." (as per Merriam-Webster).

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Note added at 2 days 23 hrs (2023-12-24 15:28:57 GMT)
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concentrato/accumulato
Note from asker:
Salve Fausto, il concetto isolatamente sembrerebbe corretto, ma nel contesto non lo capisco. "E' stato possibile incrementare selettivamente il livello di artemisinina e... accumulata dalle cellule cancerogene"? Ho sbaglio io (possibile, non è il mio campo), oppure c'è un errore nel testo. Grazie.
Peer comment(s):

agree Costanza D'Odorico
39 mins
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