geen BCR-ABL fusiegenen passend bij t(9,22)
English translation: translocation (9,22)
| 17:34 Feb 2, 2023 |
| Dutch to English translations [PRO] Medical - Medical (general) / bone marrow test results | |||||||
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|  Selected response from: Jakub Rychter, PhD Spain Local time: 03:51 | ||||||
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| 5 | tandheelkunde |
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| 4 | translocation (9,22) |
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| 3 | no BCR-ABL fusion genes consistent with the t(9;22) translocation |
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| Discussion entries: 6 | |
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Answers
10 mins confidence: 
no BCR-ABL fusion genes consistent with the t(9;22) translocation Explanation: I think you could solve it this way. Genomic instability is an important underlying pathophysiological mechanism in chronic myeloid leukemia (CML). It results in formation of the Philadelphia chromosome (Ph, t(9;22)(q34;q11)/BCR-ABL1) with various breakpoints and variant translocations, but also additional chromosomal abnormalities, and mutations in and outside the BCR-ABL1 kinase domain. Understanding the diversity of chromosomal and molecular manifestations in CML is of importance for the clinician. https://www.cmylife.nl/sites/default/files/2021-09/NTvH Gene... The hallmark of chronic myeloid leukemia (CML) is the BCR-ABL fusion gene, which is usually formed as a result of the t(9;22) translocation. https://pubmed.ncbi.nlm.nih.gov/10648381/ |
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3 mins confidence:
translocation (9,22) Explanation: https://pubmed.ncbi.nlm.nih.gov/3054349/ -------------------------------------------------- Note added at 12 mins (2023-02-02 17:47:07 GMT) -------------------------------------------------- No BCR-ABL fusion genes consistent with translocation (9,22). |
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49 mins confidence:
tandheelkunde Explanation: Hallo, Ik ben Belgisch staatsburger, geboren in Brussel. Ik ben al 40 jaar tandarts |
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