Parece en Japon, estand haciiendo TERApia de tetrodotoxina. .ncbi.nlm.nih.gov/pmc/articles/PMC6212850/ medical application of tetrodotoxin (TTX), a potent non-protein specific blocker of voltage-gated sodium (NaV) channels. The selectivity of action, lack of affinity with the heart muscle NaV channels, and the inability to penetrate the blood–brain barrier make this toxin an attractive candidate for anesthetic and analgesic drug design. The efficacy of TTX was shown in neuropathic, acute and inflammatory pain models.
consumer.healthday.com/cancer-information-5/mis-cancer-news-102/fabrican-un-poderoso-analg-eacute-sico-del-veneno-del-pez-globo-519019.

Se está estudiando un medicamento fabricado con el veneno del pez globo, para comprobar si puede aliviar el dolor del cáncer.

Los resultados preliminares indican que el medicamento, Tectin, se tolera bien y puede aliviar el dolor del cáncer por hasta dos semanas en algunos pacientes, según un estudio presentado recientemente en la reunión de la American Pain Society y la Canadian Pain Society en Vancouver, British Columbia.

Dice alli......Desde hace mucho, el pez globo, también conocido como Fugu, se conoce como una arriesgado manjar para los amantes del sushi. Sólo los más experimentados chefs de sushi preparan pez globo para los clientes, ya que el consumo de la toxina natural del animal puede causar parálisis o incluso la muerte.

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Note added at 59 mins (2023-05-08 00:54:03 GMT)
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Quien sabe? suene un poco raro, lAgree , origin of text?

links https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212850/
https://consumer.healthday.com/cancer-information-5/mis-canc...

https://onlinelibrary.wiley.com/doi/10.1002/anie.201901564 The deadly nature of the puffer fish has been known to mankind since the dawn of civilization. However, the compound responsible for this fatal activity was isolated only in the early 20th century and has been widely known to the scientific community as tetrodotoxin since then. This review traces its history, isolation, structural elucidation, biology, and synthesis. The syntheses of unnatural derivatives are covered as well.