English to Greek Medical Medical (general)

Clinical development is split into three phases: I, II, and III. After the completion of Phase I, the first trials in humans (with approximately 20 to 100 participants), phase IIa begins with a proof of concept study. Phase IIa usually sees testing in 100 to 500 participants. When the Proof of Concept has been confirmed, Phase IIb begins, with clinical trials of between 1,000 and 5,000 participants,