Feb 2, 2021 18:16
3 yrs ago
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English term
was approximately 750-fold based on exposure
English to Russian
Medical
Medical: Pharmaceuticals
At the highest dose, the margin of safety was approximately 750-fold based on exposure (AUC) in humans following an intravitreal injection of 2.0 mg ХХХХ.
Based on this study, the no‑observed-adverse-effect level (NOAEL) for OPT‑302 was considered to be 10 mg/kg/day in rats.
Based on this study, the no‑observed-adverse-effect level (NOAEL) for OPT‑302 was considered to be 10 mg/kg/day in rats.
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резерв безопасности в расчете на экспозицию (AUC) был примерно в 750 раз выше, чем у человека, получившего ....
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