Glossary entry (derived from question below)
English term or phrase:
gene silencing
Turkish translation:
gen susturma
Feb 9, 2010 12:55
14 yrs ago
English term
gene silencing
GBK
English to Turkish
Science
Biology (-tech,-chem,micro-)
Definition from
MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells.
Example sentences:
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
Proposed translations
(Turkish)
5 +2 | gen susturma | Murat Uzum |
Change log
Feb 9, 2010 12:54: changed "Kudoz queue" from "In queue" to "Public"
Feb 9, 2010 12:55: changed "Stage" from "Preparation" to "Submission"
Feb 12, 2010 13:55: changed "Stage" from "Submission" to "Selection"
Feb 19, 2010 14:54: changed "Stage" from "Selection" to "Completion"
Proposed translations
+2
41 mins
Selected
gen susturma
Definition from
Google Documents:
Birçok tıbbi makalede bu şekilde dilimize girmiştir.
Example sentences:
Ortadoğu Teknik Üniversiteli (ODTÜ) araştırmacılar, tahılda rekoltenin düşmesine neden olan buğdayda sarı pas, arpada külleme hastalığında rol alan bir genin işlevini gen susturma yöntemiyle tanımlamayı başardı. (Genç Ziraat)
ABD'li ve Alman bilim adamları, insan vücudunun yapıtaşlarından RNA sayesinde 'gen susturma' adı verilen yöntemle hastalıklı genlerin 'kapatılabileceğini' açıkladı. (Gen Bilim)
RNA interferans, çift iplikçikli RNA'nın hücreye girdiğinde homoloğu olan mRNA'nın yıkılması ile sonuçlanan transkripsiyon sonrası gen susturma mekanizmasıdır (Pamukkale Üniversitesi SBE)
4 KudoZ points awarded for this answer.
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